14 Applications. The brand recommended by more gynecologists. Replenishes vaginal moisture for days. Estrogen-Free, fragrance free. Non-Staining, non-irritating. Clinical studies prove that Replens actually replenishes your natural moisturizers for days at a time, and with regular use. Replens provides continuous vaginal moisture for most women. Each dose provides long-lasting comfort which lasts for days. Replens is the No. 1 recommended choice by gynecologists for relieving vaginal dryness.